Tuesday, March 5, 2013

Zit microbiomes

Can't help but love the title, eh? So these researchers did microbial analysis both of skin from clear-skinned students and skin from acne-ridden students. The main bacterium Proprionibacteium acne was present on both but when they did genomic analysis they were able to detect strain-level differences. What was different about the two?

P. acne on acne-ridden students: contained "gene islands" associated with skin issues. A "gene island" is a series of genes in the genome that are in the same segment, associated with some particular process, and are often times thought to have entered the genome via some kind of genetic event.

P. acne on healthy skinned-students had genes that had something to do with viral blocking (the secondary source I was reading was not very detailed on this)

current students will find the last couple of paragraphs in the secondary summary articel at Biotechniques to be interesting. Read it and see if you can see Koch's Postulates popping up

Here's the primary resource if anyone wants to follow up on this

Fitz-Gibbon et al. Journal of Investigative Dermatology aop, (2013) | doi:10.1038/jid.2013.21.


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